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				<title>CEM Corporation : Forum / topic</title>
				<link>http://www.cem.com/</link>
				<description>CEM Corporation, a private company based in Matthews, North Carolina, is the leading provider of microwave laboratory instrumentation. The Company has subsidiaries in the United Kingdom, Germany, Italy and France, as well as a global network of distributors. CEM designs and manufactures systems for life sciences, synthetic chemistry, analytical chemistry, and processing plants worldwide. The Company's products are used in many industries including pharmaceutical, biotech, chemical, environmental, and food processing, as well as for academic research.</description>

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				<copyright>All content Copyright 2009 CEM Corporation<a href="{e_PLUGIN}content/content.php?content.12">CEM is an official GSA Supplier</a> | <a href="http://cem.com/pdf/94160f CEMCorp.pdf">ISO certification since 1994</a> | <a href="{e_BASE}page97.html">Privacy Policy</a> | <a href="{e_PLUGIN}rss_menu/rss.php">RSS Feeds</a></copyright>
				<managingEditor>rich.davis@nospam.com (Admin)</managingEditor>
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				<pubDate>Thu, 09 Sep 2010 03:27:50 -0600</pubDate>
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<pubDate>Wed, 31 Dec 1969 17:00:00 -0700</pubDate>
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<description><![CDATA[I am interested in incoporating microwave instrumentation into my undergraduate teaching lab. Can anyone share their experience?]]></description>
<author>keller.barnhardt@nospam.com (Keller)</author>
<pubDate>Tue, 09 Mar 2010 02:19:46 -0700</pubDate>
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<description><![CDATA[Hello All!<br /><br />Welcome to CEM's newest feature- a Microwave Synthesis Forum exclusively for our colleagues in the acdemic world to discuss real world applications of microwave enhanced chemistry in teaching and research! If you would like, you can introduce yourself here to our online community. Alternatively, feel free to jump right into the discussions by posting in a thread that you create, or an existing one that catches your interest!<br /><br />Let the collaboration begin!]]></description>
<author>Ashley.Lewis@nospam.com (Ashley)</author>
<pubDate>Thu, 11 Mar 2010 03:03:45 -0700</pubDate>
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<description><![CDATA[Hey Everyone-<br /><br />I was curious, how many of you are using the Organic Chemistry curriculum in your teaching labs now? Are you using the curriculum as written, or are you creating your own experiments using the provided experiments as guidelines?  Please answer the poll below- and feel free to elaborate in the thread! (ie: which experiments do you use, how/why you deviate from the written experiments)]]></description>
<author>Ashley.Lewis@nospam.com (Ashley)</author>
<pubDate>Thu, 11 Mar 2010 04:24:01 -0700</pubDate>
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<description><![CDATA[What system are you all using in your labs? Are you using it for teaching, research or a combination of both?]]></description>
<author>Ashley.Lewis@nospam.com (Ashley)</author>
<pubDate>Thu, 11 Mar 2010 04:32:49 -0700</pubDate>
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<description><![CDATA[In a recent poll of current CEM users in academia there was significant interest in using microwave synthesizers in undergraduate teaching labs for inorganic chemistry courses. Unlike organic chemistry courses which generally teach from common traditional organic reaction schemes, inorganic labs do not often work from a small subset of reactions. As a result, I am interested in hearing from the "front lines" of the teaching laboratories and see what new is going on in the Inorganic teaching sector!<br /><br />Have any of you developed any Inorganic reactions you would like to share? If so, please do! Also feel free to share how you incorporated these labs into your cirrculum.]]></description>
<author>Ashley.Lewis@nospam.com (Ashley)</author>
<pubDate>Thu, 11 Mar 2010 04:42:32 -0700</pubDate>
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<description><![CDATA[As avid users of microwave chemistry we always go to the microwave first when trying out new chemistry. I would love to hear what things people are trying in their units and getting some discussion going. I think we can help each other using this forum. We all have hints and tips I think we can share.]]></description>
<author>nicholas.leadbeater@nospam.com (Nicholas Leadbeater)</author>
<pubDate>Thu, 18 Mar 2010 09:23:16 -0600</pubDate>
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<description><![CDATA[CEM is excited to welcome you to the Microwave Peptide Synthesis Discussion forum.  This is a place where we can come together as a community and discuss all aspects of microwave-enhanced peptide synthesis. <br /><br />Please feel free to start a topic to discuss any question you have, or respond to another thread with advice and insight.  Our goal is to foster open discussion that will allow everyone to share their experiences and learn from each other about all aspects of microwave peptide synthesis.]]></description>
<author>eric.williamson@nospam.com (Eric)</author>
<pubDate>Wed, 21 Apr 2010 14:21:30 -0600</pubDate>
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<description><![CDATA[I have a CEM Gas Addition Kit in my laboratory but no means of evacuating the vessel prior to introducing the gas (hydrogen, CO, argon, etc). The tubing diameter on the Gas Addition Kit is very small and none of the commercial vacuum pumps I have found are suitable. I am curious to know what others are using for this purpose. Our Gas Addition Kit is sitting unused until this is resolved.<br /><br />Aaron]]></description>
<author>reynolds@nospam.com (drajreynolds)</author>
<pubDate>Wed, 21 Apr 2010 14:39:03 -0600</pubDate>
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<description><![CDATA[As Technical Coordinator, I answer a lot of questions from our users.  The most common question people ask me is what resins are "best" for the microwave. <br /><br />For acids, there's always Wang, and we've had success with CLEAR and NovaSYN TGA.  For amides, we've seen great purity from PAL-PEG PS and Rink Amide MBHA.<br /><br />Does anyone have a favorite resin they've gotten good results with?]]></description>
<author>eric.williamson@nospam.com (Eric)</author>
<pubDate>Thu, 22 Apr 2010 09:01:52 -0600</pubDate>
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<description><![CDATA[As satisfied Liberty user since 2004 I am always thinking about buying a new system (currently we have only 2 in our labs).<br /><br />Unfortunately the price for Liberty 1 is a lot lower and that has already influenced our CFO not to buy the 12-channel-system.<br /><br />I am wondering wether anybody has experience with the half-life-time of the reaction vessels on Liberty 1. In the past we often had problems with leakages of the reaction vessel - as we do not open or even touch it anymore these problems are gone now. In case one has to open it very often I can imagine that these problems with leakages of the vessel become an issue again.<br /><br />Any experience with that?<br /><br />Lex]]></description>
<author>arybka@nospam.com (Lex Luger)</author>
<pubDate>Thu, 22 Apr 2010 20:05:55 -0600</pubDate>
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<description><![CDATA[Hello. I have 'inherited' a Discover 908010 system after taking over an old lab and although I have an instruction manual, I can't seem to work out how to get it to heat a closed vessel to 120°C for a fixed length of time. It seems to reach the required temperature and then cut off and gradually cool down, so I end up with only 30 seconds or so of heating.<br /><br />Thanks in advance for any help.<br /><br />Chris]]></description>
<author>c.welch@nospam.com (ChrisW)</author>
<pubDate>Fri, 23 Apr 2010 01:56:05 -0600</pubDate>
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<description><![CDATA[I have been making a slew of membrane proteins on the LIberty and love the quickness. Most peptides are about 23aa but have made up to 52 aa's. I have seen a pretty significant variation in the amount of peptide obtained after cleavage of the same peptide once made. I would like to optimize the max. amount of pure peptide out the back end. Would anyone venture a guess of the best coupling agents or resins for membrane proteins? I normally use a PBF resign with HBTU and HATU. <br />Cheers,<br />Dan]]></description>
<author>mayodj@nospam.com (D. Mayo)</author>
<pubDate>Tue, 27 Apr 2010 05:39:55 -0600</pubDate>
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<description><![CDATA[Hi;<br />i joined a group having 12 channel machine. i wonder how many residues i can go for within one peptide chain? and what is the protocol  i should follow?<br /><br />thanks]]></description>
<author>ahmedshaheen75@nospam.com (shaheen)</author>
<pubDate>Mon, 10 May 2010 05:45:24 -0600</pubDate>
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<description><![CDATA[In the labs here at CEM, we're tried many different activators over the years, and we've found every activator we've tried has performed well in the microwave.  Which activators have you tried, and what's become your favorite activator?]]></description>
<author>eric.williamson@nospam.com (Eric)</author>
<pubDate>Fri, 30 Apr 2010 02:03:53 -0600</pubDate>
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<description><![CDATA[Hello:<br /><br />i notice during my calculation using pepDriver software calculator that no mater what the scale of my synthesis, still the concentration of the activator at 0.5 M and aa at 0.2M. i wonder if this normal or i am missing something during calculation. how the machine adjust the amount of activator and aa for different scales? and if the machine does this, should the concentration of high scale become more diluted than the low one??]]></description>
<author>ahmedshaheen75@nospam.com (shaheen)</author>
<pubDate>Mon, 17 May 2010 02:21:40 -0600</pubDate>
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<description><![CDATA[Well I thought it could be a god idea to have a thread where people can exchange experience concerning error issues and troubleshooting.  So I'll go first :] Lately our yields have been quite low and we have had some error messages upon deprotect addition. <br /><br />The service technician will not be able to be here untill another 2 weeks, so any help is appriciated. Erik]]></description>
<author>holm@nospam.com (Erik holm Nielsen)</author>
<pubDate>Thu, 03 Jun 2010 08:20:01 -0600</pubDate>
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<description><![CDATA[Hi<br />I have heard a lot of good things about the Chemmatrix resins, so now I've ordered some.<br />However I'm concerned with the swelling of the Chemmatrix resin, as you want the resin to be completely soluted during the various steps. So as the swelling of the Chemmatrix resin is around twice as big as for PS resin, I'm wondering whether it is necessary to take any precautions when using this resin?<br /><br />In advance thanks<br />Erik]]></description>
<author>holm@nospam.com (Erik holm Nielsen)</author>
<pubDate>Sun, 06 Jun 2010 20:39:56 -0600</pubDate>
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<description><![CDATA[well, During conventional stepwise Fmoc-based solid phase peptide synthesis, base-catalyzed acylation methods lead to considerable racemization of Cys(Trt)- assembled peptide fragments during the activation/coupling process (same with His), lower temperatures helps to avoid it. However,  people suggest to use other kind of couplig conditions like using DIC non base-catalyzed and room temperature, could we use this coupling conditions in microwave synthesis at 55ªC?]]></description>
<author>lanpip2001@nospam.com (lanpip)</author>
<pubDate>Wed, 09 Jun 2010 03:51:26 -0600</pubDate>
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<description><![CDATA[Hi<br />I just downloaded the latest version of the usermanual for the 12C Liberty, and I just had a glance at it. I seem to recall that somewhere it says that the resin mesh size to be used with the LIberty should be 100-200. Can anybody confirm this.<br /><br />In advance thanks<br />Erik]]></description>
<author>holm@nospam.com (Erik holm Nielsen)</author>
<pubDate>Thu, 03 Jun 2010 21:22:58 -0600</pubDate>
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<description><![CDATA[Hi<br />As we are several users of the CEM-liberty, it would be a great if everyone could have their personal folder containg their own methods. Is this possible and how about subfolders in the sequence and cycles editor, is that possible?<br /><br /><br />In  advance thanks<br />Erik]]></description>
<author>holm@nospam.com (Erik holm Nielsen)</author>
<pubDate>Sun, 20 Jun 2010 20:45:36 -0600</pubDate>
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<description><![CDATA[I'm am planning to perform a MW synthesis using diethylene glycol monomethyl ether but was curious to know what other high boiling point solvents I could use that would act the same under MW conditions. Does anyone have experience using glycol ethers as solvents? The reaction would be run at 180 degrees for 10 mins.]]></description>
<author>s3163715@nospam.com (Dean Sheard)</author>
<pubDate>Tue, 31 Aug 2010 18:43:17 -0600</pubDate>
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<description><![CDATA[using synergy, is it possible to cool the reaction at a fixed rate after heating? for example heating to 110 for 20 mins and then cooling at 0.1 degrees celcius per minute back to room temp. this would be useful for crystallising out my product.<br /><br />david gabb]]></description>
<author>dagabb@nospam.com (croningp)</author>
<pubDate>Wed, 08 Sep 2010 03:26:01 -0600</pubDate>
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